ACTA VETERINARIA ET ZOOTECHNICA SINICA ›› 2016, Vol. 47 ›› Issue (1): 10-15.doi: 10.11843/j.issn.0366-6964.2016.01.002

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Progress in Development of African Swine Fever Vaccine

GE Sheng-qiang#,WU Xiao-dong#,ZHANG Zhi-cheng,ZHANG Yong-qiang,ZHAO Yong-gang,WANG Zhi-liang*   

  1. (China Animal Health and Epidemiology Center,Qingdao 266032,China)
  • Received:2015-03-04 Online:2016-01-23 Published:2016-01-23

Abstract:

African swine fever(ASF) is an acute,febrile,highly contagious,tick borne disease caused by African swine fever virus.The virus mainly replicate in the reticuloendothelial cells and mononuclear macrophage,resulting in cell apoptosis and causing serious impact on the immune system of the host.Even though the disease was first described in 1921,there is still no efficient vaccine available in the market because of the big virus genome,multi genotype and easily mutation.Even so,foreign scientists keep researching on the development of ASF vaccine.Although there are Chinese articles on ASF had been published,most of these articles provided brief introductions of the disease without fully discussed the development associated with ASF vaccine.Here,in order to provide reference to the research of ASF vaccine,we reviewed the current research progress of ASF vaccine.

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